
Scientists Reveal How DNA And Diet Contributed To 117-Year-Old Woman’s Longevity
At 117 years old, Maria once held the title of the world’s oldest living person.

It’s natural to wonder what it takes to live a long, healthy life - not just adding years but feeling good in those years. We’ve all heard stories of people who reach incredible ages and wonder if there’s a secret recipe behind their longevity.
Recently, researchers decided to dig deeper into one of these extraordinary lives: that of Maria Branyas Morera, who lived to be 117 years old. By examining her DNA, gut health, daily habits, and the simple choices she made every day, scientists hope to uncover clues that could help anyone looking to extend not only their lifespan but also their health span.
Maria Branyas Morera passed away in August 2024 in Spain, holding the Guinness World Record for the oldest living person since January 2023. While reaching such an age is exceptionally rare, Maria’s lifestyle and biology offer insights into factors that may contribute to a longer life.
Researchers at Barcelona University analyzed her microbiome, the community of bacteria living in her gut, and her genetic makeup, discovering a unique combination of traits that kept her body functioning like that of someone much younger.
According to Manel Esteller, a genetics professor leading the study, Maria’s genome appeared to slow her biological aging by about 17 years compared to her chronological age.
In other words, at 117, she had the biological health markers of someone around 100 years old. Remarkably, her gut microbiome resembled that of a child, which researchers believe could play a role in supporting robust immunity and metabolic health.
Maria Branyas Morera holds the title of the world’s oldest woman, exemplifying extraordinary longevity.
Maria’s daughter, Rosa Moret, said her mother rarely got sick. She noted that it wasn’t until the very end of her life that she experienced declines in vision, hearing, and memory. Even then, these changes happened slowly, suggesting a sustained period of good health rather than a sudden drop-off.
Lifestyle factors appear to have complemented Maria’s genetic advantages. She followed a Mediterranean diet, rich in fruits, vegetables, whole grains, olive oil, and moderate dairy, eating three yogurts every day. She never smoked or drank alcohol, habits commonly linked to poorer health outcomes. Instead, Maria walked regularly, maintained an active daily routine, and prioritized spending time with family and friends.

Researchers at Barcelona University analyzed the microbiome and DNA of 117‑year‑old Maria Branyas Morera, uncovering that she possessed a “child‑like microbiome” alongside a “privileged genome.”
The research team also measured Maria’s health markers and found ideal cholesterol levels, excellent blood sugar regulation, and a balanced immune response. While these indicators typically decline with age, Maria’s values stayed in healthy ranges well into her second century of life.
Beyond offering a glimpse into the biology of aging, Maria’s case challenges the notion that getting older must mean becoming frail or sick. Researchers hope that understanding how her genes and lifestyle choices interacted could inform new anti-aging treatments and dietary recommendations aimed at preserving health as we age.

Born on March 4, 1907, in San Francisco to Spanish and Mexican parents, Maria moved back to Spain with her family in 1915. She spent most of her life in Catalonia, experiencing the upheavals of the 20th century while building deep social connections and maintaining simple, healthy habits.
After Maria’s passing, the title of the world’s oldest living person now belongs to Inah Canabarro Lucas, a Brazilian nun aged 116. While surpassing 100 years of age remains exceptional, Maria’s story shows that a combination of genetics, diet, movement, and meaningful relationships may help anyone looking to age well.

Damjan
